What local anesthetics contain sulfites?

What local anesthetics contain sulfites?

Recently, the injectable local anesthetics procain and novacain which contain sulfites have been shown to cause allergic reactions. The most commonly used local anesthetics, the amide types, do not contain sulfites unless combined with epinepherine, a hormone used to prolong the effects of anesthetics.

What if patient is allergic to local anesthesia?

Symptoms of toxic reaction include convulsions, hypotension, and bradycardia, and in some cases, it may lead to cardiovascular collapse, coma, and even death. Among the adverse effects of local anesthetics, autonomic responses include sweating, dizziness, nausea, and mild tachycardia [6].

What dental local anesthetic can be used with sulfa allergy?

Articaine HCl may safely be administered to patients with sulfur allergy. Introduced in 1975, and presently available in approximately 131 countries, there have been no reported cases of allergy to articaine HCl.

Which local anesthetics cause allergic reactions?

Ester local anesthetics are associated with a higher incidence of allergic reactions due to one of their metabolites, para-amino benzoic acid (PABA). PABA is structurally similar to methylparaben.

Does epinephrine contain sulfites?

“In patients with a definitive history consistent with anaphylactic or anaphylactoid reactions to sulfites,avoidance of medications, including epinephrine, which contain metabisulfites as preservatives might be indicated.”

Can you be allergic to dental anesthetic?

Allergic responses to the amide local anaesthetics used in dentistry are extremely rare. Many series of patients investigated for ‘suspected allergy’ have been reported,4,5,6 but in the vast majority of cases, hypersensitivity to the local anaesthetic agents was excluded.

How do I know if I’m allergic to sulfites?

Symptoms of a sulfite allergy include:

  1. Hives and itchiness.
  2. Upset stomach, diarrhea, and vomiting.
  3. Trouble swallowing.
  4. Flushing.
  5. Dizziness.
  6. Drop in blood pressure.
  7. Trouble breathing.

Are there people who are allergic to sulfites?

One percent of people are allergic to Sulfites. As mentioned in the previous blog, Sulfites (Metabisulfite and Sodium bisulfites) are preservatives which prevent dental local anaesthetic from getting brown.

Is there an allergy to amide local anaesthetics?

Allergy to amide local anaesthetics is rare. Allergic reactions are most likely to occur with ester local anaesthetic agents; these are not used routinely in dentistry. Adverse effects experienced after administration of local anaesthetics may be mistaken for allergic reactions, but often there is another explanation for the symptoms.

Why do sulfites decrease the effectiveness of the local anaesthetic?

The ‘browning’ will decrease the effectiveness of the local anaesthetic. Sulfites also act as a preservative by keeping the epinephrine fresh. In the next blog, we will wrap up our series on common dental allergies.

Why are some people allergic to local anesthetics?

Allergic reactions to local anesthetic agents may occur as a result of sensitivity to 1) either the ester or amide component, 2) the methylparaben used as a preservative in the multiple dose vials, or 3) the antioxidants used in some formulations.