What type of pathogen is Down syndrome?

What type of pathogen is Down syndrome?

Trisomy 21: About 95% of people with Down syndrome have Trisomy 21. With this type of Down syndrome, each cell in the body has 3 separate copies of chromosome 21 instead of the usual 2 copies.

Is Down syndrome pathogenic?

The molecular pathogenesis of down syndrome-associated diseases and the promising potential therapeutic targets. Trisomy 21, the most common origin of Down syndrome, is an extra copy of chromosome 21 in all cells generated by a chromosomal non-disjunction during meiosis.

Which process causes Down syndrome?

Down syndrome is caused by a random error in cell division that results in the presence of an extra copy of chromosome 21. The type of error is called nondisjunction (pronounced non-dis-JUHNGK-shuhn).

What gene is responsible for Down syndrome?

Researchers believe that having extra copies of genes on chromosome 21 disrupts the course of normal development, causing the characteristic features of Down syndrome and the increased risk of health problems associated with this condition.

What causes a person to have Down syndrome?

Down syndrome is caused by a random error in cell division that results in the presence of an extra copy of chromosome 21.

Where does the chromosome 21 for Down syndrome come from?

One chromosome in each pair comes from your father, the other from your mother. Down syndrome results when abnormal cell division involving chromosome 21 occurs. These cell division abnormalities result in an extra partial or full chromosome 21.

How does mosaic Down syndrome occur in the body?

Mosaic Down syndrome occurs when some cells in the body are normal, while others have trisomy 21. Robertsonian translocation occurs when part of chromosome 21 breaks off during cell division and attaches to another chromosome, usually chromosome 14. The presence of this extra part of chromosome 21 causes some Down syndrome characteristics.

When does Down syndrome occur in a translocation?

Translocation trisomy 21: In a translocation, there are two copies of chromosome 21, but extra material from a third 21st chromosome is attached (translocated to) another chromosome. This type of Down syndrome may occur either before or after conception and is the form that may sometimes be passed down (inherited).