What is the meaning of polyclonal Hypergammaglobulinemia?

What is the meaning of polyclonal Hypergammaglobulinemia?

A polyclonal gammopathy is an abnormal increase in the production of antibodies using many different types of cells.

How is polyclonal gammopathy treated?

In general, treatment is directed at the underlying disease, but there are reports of polyclonal gammopathy leading to symptomatic hyperviscosity. In these cases, plasmapheresis and/or corticosteroids seem to be effective.

Are there any autoimmune diseases associated with polyclonal hypergammaglobulinemia?

There is no underlying infectious or inflammatory condition, and there is no evidence of an autoimmune disease or lymphatic neoplasm. The class restriction has been linked to class-specific regulatory T cell clones. The most profound polyclonal hypergammaglobulinemia is found in chronic liver disease, rheumatoid arthritis and Sjögrens syndrome.

Which is the best description of hypergammaglobulinemia?

Most cases of hypergammaglobulinemia are polyclonal gammopathies. A gammopathy is an abnormal increase in the body’s ability to produce antibodies. A monoclonal gammopathy is an abnormal increase in the production of antibodies using the same type of cell.

Are there any treatment options for hypergammaglobulinemia?

Treatment options. Since hypergammaglobulinemia is caused by other conditions, there aren’t many direct treatment options available. But you can improve or cure this condition by treating other underlying infections, immune disorders, and diseases.

What is the difference between monoclonal and polyclonal gammopathies?

Monoclonal and polyclonal gammopathies. Most cases of hypergammaglobulinemia are polyclonal gammopathies. A gammopathy is an abnormal increase in the body’s ability to produce antibodies. A monoclonal gammopathy is an abnormal increase in the production of antibodies using the same type of cell.

What causes low gamma globulin?

• Kidney diseases
• Malnutrition
• Inflammatory bowel disease
• Acute anemia
• Burns
• Certain cancers

  What is meant by polyclonal gammopathy?

  polyclonal gammopathy. a hypergammaglobulinemia resulting from an increased production of several different immunoglobulins and usually attributable to persistent, high level exposure to antigens; occur in a wide variety of infectious Infection Invasion of microorganisms such as viruses, bacteria, and protozoa. Eg: Flu, malaria, strep throat , inflammatory, and immune-mediated diseases.

  What is polyclonal gammopathy?

  polyclonal gammopathy. a hypergammaglobulinemia resulting from an increased production of several different immunoglobulins and usually attributable to persistent, high level exposure to antigens; occur in a wide variety of infectious, inflammatory, and immune-mediated diseases.