What is the indication for moxifloxacin?
What is the indication for moxifloxacin?
Moxifloxacin is used to treat certain infections caused by bacteria such as pneumonia, and skin, and abdominal (stomach area) infections. Moxifloxacin is also used to prevent and treat plague (a serious infection that may be spread on purpose as part of a bioterror attack.
Is moxifloxacin safe for heart patients?
Even in a high-risk population of elderly patients with community-acquired pneumonia (CAP), sequential intravenous/oral (IV/PO) treatment with moxifloxacin has a good cardiac rhythm safety profile, comparable to that of levofloxacin [25].
Why moxifloxacin should not be used in arrhythmic patients?
Moxifloxacin use was associated with a 1.87-fold increased risk of serious ventricular arrhythmia compared with cefixime during the first week after initiating the drug. The risk of ventricular arrhythmia was especially high in moxifloxacin users who were older or had cardiovascular disease.
Can levofloxacin cause irregular heartbeat?
If you have low blood potassium or an abnormally slow heartbeat, levofloxacin may increase your risk of having a fast, slow, or irregular heartbeat, loss of consciousness, or fainting spells. If these symptoms occur, tell your doctor right away.
What are the side effects of Avelox 400 mg?
This drug was discontinued due to side effects in 5% of patients overall, 4% of patients using 400 mg orally, 4% using 400 mg IV, and 8% using 400 mg IV/oral sequential therapy. The most common side effects leading to discontinuation with the oral dose were nausea, diarrhea, dizziness, and vomiting.
When to switch from intravenous to oral Avelox?
Intravenous formulation is indicated when it offers a route of administration advantageous to the patient (for example, patient cannot tolerate an oral dosage form). When switching from intravenous to oral formulation, no dosage adjustment is necessary.
How to measure the frequency of adverse reactions?
The frequency of an adverse reaction may be expressed in various ways and which is used will be dependent on the methodofmeasurement. The most important distinction is between absolute and relative risk. Clearly, when the effect does not occur in the absence of exposure to the drug, thefrequencyof the
What happens if you mix Avelox with fluoroquinolones?
Such interactions often affect fluoroquinolones by reducing its bioavailability and effectiveness. Interference with Avelox absorption results in lower systemic concentrations, reducing its efficiency. Because Avelox is used to treat complicated infection, reduced clinical efficacy can be fatal.