What is the generic name for protamine sulfate?
What is the generic name for protamine sulfate?
When administered alone, protamine (protamines) has an anticoagulant effect. However, when it is given in the presence of heparin (which is strongly acidic), a stable salt is formed which results in the loss of anticoagulant activity of both drugs.
Is heparin a brand name or generic?
Heparin is available as generic heparin and under other generic brand names.
Who makes protamine sulfate?
Protamine
| Name | Dosage | Labeller |
|---|---|---|
| Protamine Sulfate Inj 10mg/ml USP | Liquid | Lyphomed, Division Of Fujisawa Canada Inc. |
| Protamine Sulfate Injection USP | Liquid | Omega Laboratories Ltd |
| Protamine Sulfate Injection USP | Solution | Sandoz Canada Incorporated |
| Protamine Sulfate Injection, USP | Solution | Fresenius Kabi |
When do you give protamine sulfate?
Administration of full dose protamine is indicated in patients who need reversal less than 60 minutes after bolus administration. For patients on heparin infusions, due to the half-life of heparin, the amount of heparin administered over the previous 2 hours should be utilized to calculate a protamine dose.
What can I use instead of protamine?
Available options for anticoagulation include direct oral anticoagulants, vitamin K antagonists, thrombin inhibitors, low-molecular-weight heparins, and heparin.
What is the generic for heparin?
What are the main differences between Lovenox and heparin?
| Main differences between Lovenox and heparin | |
|---|---|
| Drug class | Anticoagulant |
| Brand/generic status | Brand and generic version available |
| What is the generic name? | Enoxaparin |
| What form(s) does the drug come in? | Solution for injection |
Is apixaban the same as heparin?
Heparin is a good anticoagulant that prevents blood clots. However, you’ll need to get frequent blood tests to make sure it’s working well. Eliquis (apixaban) is very effective in reducing the risk of stroke in people with atrial fibrilation or other clotting disorders.
How fast does protamine sulfate work?
Protamine is administered via intravenous infusion. The onset of action is rapid, with neutralization of heparin evident within 5 minutes. The duration of action can persist up to 2 hours, depending on body temperature.
How fast do you push protamine?
Administer protamine 10 mg/mL solution undiluted via slow intravenous injection. The administration rate MUST NOT exceed 50 mg over a 10 minute period. High doses and rapid administration may result in severe hypotension, cardiovascular collapse, pulmonary edema, pulmonary vasoconstriction, and pulmonary hypertension.
Is heparin and aspirin the same?
Aspirin is an anticoagulant that prevents thrombosis by the increase prostaglandin E2. It accelerates blood to placenta, which should be started from the beginning of pregnancy. Heparin has both anticoagulative and anti-inflammatory effects. Heparin does not penetrate the placenta and is harmless for fetus.
Which is the generic name for protamine sulphate?
Protamine Sulphate (Protamine Sulfate) generic is a heparin antagonist, prescribed for reversing the anticoagulant effects of heparin. * Drug Price mentioned in Indian Rupees ( ). Medispan Limited.
How long does it take to take protamine sulfate?
Protamine sulfate is a medication that is used to reverse the effects of heparin. It is specifically used in heparin overdose, in low molecular weight heparin overdose, and to reverse the effects of heparin during delivery and heart surgery. It is given by injection into a vein. The onset of effects is typically within five minutes.
When is protamine sulfate used as a blood factor?
Protamine sulfate is a blood factor used when the reversal of the anticoagulant effect of heparin is necessary and for the treatment of heparin overdose.
How many brands of protamine sulphate are there in India?
The generic Protamine Sulphate is manufactured by one company. Medindia’s drug directory has currently 5 Brands of Protamine Sulphate listed. New generics and brands are constantly being updated as and when they are approved by drug controller and available in the pharmacies. * Drug Price mentioned in Indian Rupees (). Medispan Limited.
How is protamine sulfate used for an antidote for heparin?
Protamine sulfate is a medication that is used to reverse the effects of heparin. It is specifically used in heparin overdose, in low molecular weight heparin overdose, and to reverse the effects of heparin during delivery and heart surgery. It is given by injection into a vein. The onset of effects is typically within five minutes.
What is protamine sulfate antidote for?
Protamine sulfate, a compound derived from purified fish sperm, is the antidote for heparin. Heparin is an anti-coagulant, or blood thinner, that is often given to patients prior to cardiac surgical procedures such as a cardiopulmonary bypass in order to prevent blood clots from forming.
How does protamine sulfate work?
Protamine sulfate is a naturally occurring substance that is found in the sperm of a number of species of fish. When it is extracted, it forms a white powder that is then dissolved in water to create the final solution. It generally acts quickly on any heparin present in the body, and administration does not take long.