What is hydroxyurea 500 mg used to treat?

What is hydroxyurea 500 mg used to treat?

Hydroxyurea treats cancer by slowing or stopping the growth of cancer cells in your body. Hydroxyurea treats sickle cell anemia by helping to prevent formation of sickle-shaped red blood cells.

What is hydroxyurea toxicity?

Hydroxyurea is an extremely toxic drug with a low therapeutic index. Since hydroxyurea inhibits DNA synthesis, it can result in significant toxicity, including myelosuppression. Furthermore, inhibition of DNA synthesis without affecting RNA synthesis may result in red blood cells becoming megaloblastic.

Is Hydrea used to treat high platelets?

Your doctor may suggest one of the following prescription drugs, perhaps along with low-dose aspirin, to reduce your platelet count: Hydroxyurea (Droxia, Hydrea.) This drug is the most common prescription used for essential thrombocythemia.

Is Hydrea a chemo drug?

Hydroxyurea (hydroxycarbamate, Hydrea) is a chemo drug that has helped some patients with CMML live longer. This drug comes as a capsule that’s taken by mouth daily. It can bring the numbers of white blood cells and monocytes down to normal.

What are the side effects of hydroxyurea 500 mg?

“Bad side effects (or what I would consider bad side effects and not to be tolerated) – 71 year old female, 58 kgs: been taking 500 mg a day for approx 2 and a half months. Recently experienced fever, chills, headaches, muscle aches, extreme tiredness, lack of appetite – enough that I could not function and spent days in bed.

What’s the generic name for the drug hydroxyurea?

Hydroxyurea Generic Name: hydroxyurea (hye DROX ee yoo REE a) Brand Name: Droxia, Hydrea, Mylocel, Siklos Dosage Forms: oral capsule (200 mg; 300 mg; 400 mg; 500 mg); oral tablet (100 mg; 1000 mg)

How often should I increase my Hydrea dose?

During those months, my Hydrea dose was increased from 500g daily or 7 capsules a week to 1000/1500g daily or 18 capsules per week. In those earlier days I was back every 2 weeks until the increased dosage eventually achieved the desired levels around 300.

When did my wife start taking hydroxyurea platelets?

Hi Doggy 555. My wife had platelets around 1900, when started on hydroxy, the dose was quite high at the time, and as she was in hospital enduring a major portal vein thrombosis, her blood was tested frequently. The numbers didn’t tumble downwards.

What are the inactive ingredients in Hydrea capsules?

Hydrea Description Hydrea (hydroxyurea capsules, USP) is an antimetabolite available for oral use as capsules containing 500 mg hydroxyurea. Inactive ingredients include citric acid, colorants (D&C Yellow No. 10, FD&C Blue No. 1, FD&C Red No. 40, and D&C Red No. 28), gelatin, lactose, magnesium stearate, sodium phosphate, and titanium dioxide.

When is the best time to take hydroxyurea 500 mg?

Follow all instructions closely. Take hydroxyurea capsules 500 mg at the same time of day. Take with or without food. Take with a full glass of water. Swallow whole. Do not open the capsules. Wash your hands before and after use. To gain the most benefit, do not miss doses.

Are there any side effects from hydroxyurea 500 mg?

Worse side effects from radiation treatment have happened with hydroxyurea capsules 500 mg. Allergic reactions have happened with hydroxyurea capsules 500 mg. Sometimes, these have been very bad and people have had to go to the hospital. Talk with the doctor. If you are 65 or older, use hydroxyurea capsules 500 mg with care.

When to tell your doctor about Hydrea side effects?

Tell your doctor right away if you have signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, a wound that will not heal; any bruising or bleeding; or if you feel very tired or weak.