What is Chondroradionecrosis of the larynx?
What is Chondroradionecrosis of the larynx?
Summary. Chondroradionecrosis (CRN) of the larynx is a rare and severe complication of radiotherapy and endotracheal intubation which can be fatal if not managed promptly. In recent years, the trend in oncological surgery is organ preservation even in the advanced stage of laryngeal malignancies.
What is osteoradionecrosis of jaw?
Osteoradionecrosis is bone death due to radiation. The bone dies because radiation damages its blood vessels. Osteoradionecrosis is a rare side effect that develops some time after radiation therapy has ended. It usually occurs in the lower jaw, or mandible.
What is the treatment for osteoradionecrosis?
Osteoradionecrosis (ORN) of the jaw is a significant complication of radiotherapy for oral cavity cancer. In addition to antibiotic medication, treatment options such as hyperbaric oxygen therapy, surgical approaches, and combined therapy with pentoxifylline and tocopherol have been recently introduced.
How can osteoradionecrosis be prevented?
Dental treatment prior to radiation therapy to prevent osteoradionecrosis
- All extractions should be done 3-6 weeks prior to initiation of radiation therapy to allow for adequate healing.
- Perform adequate alveoloplasty after dental extractions to eliminate sharp bony projections.
How common is osteoradionecrosis?
Perhaps the most severe side effect of radiation therapy is osteoradionecrosis (ORN), or bone death. This condition occurs in three to ten percent of patients.
How do you know if a bone is dying?
As bone damage worsens, you may have the following symptoms:
- Pain in the joint that may increase over time and becomes severe if the bone collapses.
- Pain that occurs even at rest.
- Limited range of motion.
- Groin pain, if the hip joint is affected.
- Limping, if the condition occurs in the leg.