Popular guidelines / 31/08/2020

What is better firmagon vs Lupron?

Lupron Depot initially increased testosterone levels—65% by the third day, compared to a 94% reduction with FIRMAGON. Some patients may require additional medication to prevent a symptomatic flare with Lupron Depot.

How long is Lupron effective for prostate cancer?

Lupron controls prostate cancer for an average duration of 18 to 24 months in men with metastatic disease. When Lupron stops working, other hormonal agents such as Casodex or Nilandron may provide temporary control, but their duration of effect (keeping the PSA down) usually lasts for less than a year.

Does testosterone return after Lupron?

When a person first starts treatment with Lupron, they may have a testosterone flare. Later on, they may experience side effects due to having very low testosterone levels in their body. After treatment stops, testosterone levels begin to return to normal.

What can you take instead of Lupron?

Alternatives to Trelstar

leuprolide (Eligard, Lupron Depot)
goserelin (Zoladex)
degarelix (Firmagon)
histrelin (Vantas)

Does Lupron affect the liver?

Despite use for several decades, leuprolide has not been linked to convincing cases of clinically apparent liver injury. Routine monitoring of patients for liver test abnormalities is not recommended. Likelihood score: E (unlikely cause of clinically apparent liver injury).

Is there a Lupron shortage?

The shortage is temporary, and the safety and efficacy of LUPRON DEPOT were not compromised. Should you require any additional information, please contact our Customer Service Department at 1-888-704-8270.

Are there any alternative to orchiectomy for prostate cancer?

Estrogens (female hormones) were once the main alternative to orchiectomy for men with advanced prostate cancer. Because of their possible side effects (including blood clots and breast enlargement), estrogens have been replaced by other types of hormone therapy.

Which is better orchiectomy or LHRH for prostate cancer?

Average (median) management costs for the first 12 months after prostate cancer diagnosis were similar for the two sets of patients. [LHRH] agonist therapy is associated with higher risks of several clinically relevant adverse effects compared with orchiectomy.

What happens if you stop taking Lupron for prostate cancer?

If Lupron treatment is stopped, testosterone levels can rise and your cancer may worsen. Do not discontinue Lupron Depot unless your doctor tells you to stop treatment. In men, testosterone is reduced to castrate concentrations with Lupron Depot treatment.

Are there any side effects to Lupron Depot injection?

Initially, testosterone levels may rise the first weeks of treatment after Lupron Depot injection, causing a flare of side effects, such as pain or urinary symptoms. Your doctor may prescribe antiandrogen agents like bicalutamide (Casodex) or flutamide (Eulexin) to help reduce this flare. This is not a complete listing of side effects.

What are the pros and cons of Lupron?

A number of medical experts now state that the risks of Lupron outweigh its benefits. Lupron is used for treating several diseases. In children, the medication is used to treat the early onset of puberty. In men, the drug is given to treat symptoms of prostate cancer.

Are there any psychological effects of an orchiectomy?

There is no doubt that there can be significant psychological harms associated with a surgical orchiectomy for many men (above and beyond the loss of “maleness” caused by a massive reduction in serum testosterone).