What is another name for hypogonadotropic hypogonadism?

What is another name for hypogonadotropic hypogonadism?

Hypogonadotropic hypogonadism (HH), is due to problems with either the hypothalamus or pituitary gland affecting the hypothalamic-pituitary-gonadal axis (HPG axis)….

Is Klinefelter hypogonadotropic hypogonadism?

Klinefelter’s syndrome is characterized by hypergonadotropic hypogonadism, 47,XXY karyotype, gynecomastia, azoospermia and testicular atrophy with hyalinization of seminiferous tubules and hyperplasia of Leydig cells.

What causes Hypergonadotropic hypogonadism?

Hypergonadotropic hypogonadism and infertility/subfertility in both sexes are the result of gonadotropin resistance caused by inactivating mutations in receptors of the two gonadotropins, LH and FSH. Both LHR and FSHR are members of GPCR family.

Is hypogonadotropic hypogonadism primary or secondary?

Impaired testicular function, i.e., hypogonadism, can result from a primary testicular disorder (hypergonadotropic) or occur secondary to hypothalamic-pituitary dysfunction (hypogonadotropic). Hypogonadotropic hypogonadism can be congenital or acquired.

Is Hypergonadotropic hypogonadism hereditary?

IHH can be congenital or acquired. The great majority of hereditary causes of IHH are congenital. Typically, in girls there is no clinical manifestation of IHH before the early teen years.

What are common causes of hypogonadism?

Causes of Hypogonadism. Primary hypogonadism causes can include aging, autoimmune disorders such as Addison’s disease and hypoparathyroidism, genetic disorders such as Klinefelter syndrome (congenital abnormality of the sex chromosomes), liver and kidney diseases, undescended testes, chemotherapy or radiation exposure, and surgery on the sex organs.

What are the types of hypogonadism?

There are two types of hypogonadism: primary and central. Primary hypogonadism means that you don’t have enough sex hormones in your body due to a problem in your gonads. Your gonads are still receiving the message to produce hormones from your brain, but they aren’t able to produce them.

What causes congenital hypogonadism?

ANSWER Congenital hypogonadism is present at birth and can be caused by a variety of inherited conditions. Among males, the most common congenital cause of hypogonadism is called Klinefelter syndrome , an abnormality of the X- and Y-chromosomes, which determine sexual characteristics.

What does hypogonadism stand for?

Hypogonadism means diminished functional activity of the gonads—the testes or the ovaries—that may result in diminished production of sex hormones. Low androgen (e.g., testosterone) levels are referred to as hypoandrogenism and low estrogen (e.g., estradiol) as hypoestrogenism.