What are the usual signs of acute phenytoin toxicity?

What are the usual signs of acute phenytoin toxicity?

Unsteady gait, dizziness/vertigo, nausea/vomiting, general weakness, and drowsiness were the most common presenting symptoms.

What happens when your Dilantin level is too high?

Dilantin, or phenytoin, toxicity happens when you have high levels of Dilantin in your body that become harmful. Dilantin is a medicine that is used to prevent and treat seizures. Dilantin toxicity can lead to a coma.

Can phenytoin cause fever?

The agents most commonly associated with causing fever include the penicillins, cephalosporins, antituberculars, quinidine, procainamide, methyldopa, and phenytoin.

How long does it take for Dilantin to leave your system?

The plasma half-life in man after oral administration of phenytoin averages 22 hours, with a range of 7 to 42 hours. Steady-state therapeutic levels are achieved at least 7 to 10 days (5–7 half- lives) after initiation of therapy with recommended doses of 300 mg/day.

What is test for phenytoin toxicity?

Phenytoin blood testing is ordered because phenytoin blood levels must be maintained within a narrow therapeutic range. If levels are too low, the affected person may experience seizures; if they are too high, the person may experience symptoms associated with phenytoin toxicity.

Does amoxicillin give you a fever?

Fever. Fevers are a common side effect of many medications, including antibiotics. A fever may occur because of an allergic reaction to a medication or as a bad side effect.

What are the adverse effects of phenytoin?

Common side effects

  • headaches.
  • feeling drowsy, sleepy or dizzy.
  • feeling nervous, unsteady or shaky.
  • feeling or being sick (nausea or vomiting)
  • constipation.
  • sore or swollen gums.
  • mild skin rash.

    Are there any medical conditions that cause disorientation and fever?

    There are 135 conditions associated with confusion, disorientation, dizziness and fever. The links below will provide you with more detailed information on these medical conditions from the WebMD Symptom Checker and help provide a better understanding of causes and treatment of these related conditions.

    Is it normal for a child to vomit yellow fluid?

    Vomiting that is bright green is most often bile. Unless your child drank a green liquid, this is not normal. It can mean the intestines are blocked up. This is a surgical emergency. Note: Vomiting some yellow fluid is normal. The yellow color is from stomach acid. Press on your child’s belly while she is distracted by a toy or book.

    What causes confusion, dizziness and fever in children?

    Dehydration, or not getting enough fluid, causes dry and sticky mouth, tearless crying, and more in children. A drug overdose can be fatal and causes sleepiness, confusion, coma, vomiting, and other symptoms. An insulin reaction is the result of low blood sugar and causes anxiety, hunger, shaking, dizziness, and more.

    What are the symptoms of disorientation and delirium?

    Overview. Disorientation is an altered mental state. A person who’s disoriented may not know their location and identity, or the time and date. It’s often accompanied with other symptoms such as: confusion, or being unable to think with your normal level of clarity. delirium, or being confused and having disrupted attention.