What are the signs and symptoms of multicentric reticulohistiocytosis?
What are the signs and symptoms of multicentric reticulohistiocytosis?
Multicentric reticulohistiocytosis (Fig. 170.3) is a rare disorder characterized by the insidious onset of polyarthritis, which often evolves into a severe erosive deforming arthritis, and distinctive small, firm cutaneous papules and nodules on the skin. Skin lesions are pleomorphic, may be pruritic, and often occur around the joints.
Is there a cure for Multicentric reticulohistiocytosis?
Although no specific therapy has consistently been shown to improve multicentric reticulohistiocytosis, many different drugs have been used. [3] For instance, therapy with non-steroidal anti-inflammatory agents (e.g., aspirin or ibuprofen) may help the arthritis .
Which is a rare arthropam form of reticulocytosis?
Multicentric reticulohistiocytosis is a very rare multisystem arthropathic form of reticulocytosis. Reticulohistiocytoses are a type of non- Langerhans cell histiocytosis. Multicentric reticulohistiocytosis is characterised by skin and mucosal lesions, and arthritis [1].
Which is the best antimalarial for Multicentric reticulohistiocytosis?
Systemic corticosteroids and/or cytotoxic agents, particularly cyclophosphamide, chlorambucil, or methotrexate, may affect the inflammatory response, prevent further joint destruction, and cause skin lesions to regress. Antimalarials (e.g., h ydroxychloroquine and mefloquine) have also been used.
What kind of disease is multicentric reticulohistiocytosis?
Multicentric reticulohistiocytosis is a disease that is characterized by the presence of papules and nodules and associated with arthritis mutilans.
Multicentric reticulohistiocytosis is a very rare multisystem arthropathic form of reticulocytosis. Reticulohistiocytoses are a type of non- Langerhans cell histiocytosis. Multicentric reticulohistiocytosis is characterised by skin and mucosal lesions, and arthritis [1].
Systemic corticosteroids and/or cytotoxic agents, particularly cyclophosphamide, chlorambucil, or methotrexate, may affect the inflammatory response, prevent further joint destruction, and cause skin lesions to regress. Antimalarials (e.g., h ydroxychloroquine and mefloquine) have also been used.