What are the immediate effects of propofol?
What are the immediate effects of propofol?
Side effects include: General anesthesia or MAC sedation: Bradycardia, arrhythmia, tachycardia, hypotension, hypertension, movement, burning/stinging, pain at injection site, apnea, rash, pruritus. ICU sedation: Bradycardia, decreased cardiac output, hypotension, hyperlipidemia, respiratory acidosis (during weaning).
What are the effects of propofol?
Common propofol side effects may include: mild itching or rash; fast or slow heart rate; or. slight burning or stinging around the IV needle.
Why is propofol given slowly?
The administration of DIPRIVAN should be initiated as a continuous infusion and changes in the rate of administration made slowly (greater than 5 min) in order to minimize hypotension and avoid acute overdosage (see DOSAGE AND ADMINISTRATION).
What is contraindicated when giving propofol?
Propofol is contraindicated in any patient that has any known hypersensitivity reaction to the drug. Caution should be taken in any patient with abnormally low blood pressure. Some package inserts state that propofol should not be given to those with reported allergies to eggs, egg products, soy, or soy products.
How long does propofol take to wear off?
The half-life of elimination of propofol has been estimated to be between 2 and 24 hours. However, its duration of clinical effect is much shorter, because propofol is rapidly distributed into peripheral tissues. When used for IV sedation, a single dose of propofol typically wears off within minutes.
What happens to your body when you take propofol?
You will relax and fall asleep very quickly after propofol is injected. Your breathing, blood pressure, oxygen levels, kidney function, and other vital signs will be watched closely while you are under the effects of propofol.
What are the side effects of propofol in the ICU?
ICU sedation: Bradycardia, decreased cardiac output, hypotension, hyperlipidemia, respiratory acidosis (during weaning).
How does propofol affect vascular capacitance in humans?
Although arterial hypotension occurs frequently with propofol use in humans, its effects on intravascular volume and vascular capacitance are uncertain. We hypothesized that propofol decreases vascular capacitance and therefore decreases stressed volume.
What happens to the BIS with increased propofol?
The BIS decreased with increasing propofol Cb to 54 (13), 39 (8), and 29 (7), respectively. Increasing concentrations of propofol led to venous dilatation as venous resistance decreased. Arterial resistance decreased in a similar manner, because the ratio between Ra and Rvr did not change significantly.
Does propofol cause brain damage?
Brain damage is found among people who take Propofol, especially for people who are male, 60+ old , have been taking the drug for < 1 month, also take medication Fentanyl , and have Sedation.
Does propofol cause low blood pressure?
Common side effects of propofol include low blood pressure, low heart rate, difficulty breathing, and local irritation at the injection site. Propofol can also cause dizziness.
Does felopio have side effects?
Blurred vision. chest pain, tightness, or heaviness. confusion. congestion. cough producing mucus. diarrhea. dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly. fast, slow, or irregular heartbeat.
Can propofol cause hearing loss?
Hearing loss is found among people who take Propofol, especially for people who are female, 40-49 old, have been taking the drug for < 1 month. The phase IV clinical study is created by eHealthMe based on reports of 25,702 people who have side effects when taking Propofol from the FDA, and is updated regularly.