How is subacute cutaneous lupus diagnosed?
How is subacute cutaneous lupus diagnosed?
How is subacute cutaneous lupus erythematosus diagnosed? SCLE can be diagnosed clinically, supported by the results of blood tests and a skin biopsy. La/SSB, dsDNA, anti-histone, and Sm antibodies are less common.
What causes subacute cutaneous lupus?
Subacute cutaneous lupus erythematosus (SCLE) occurs in genetically predisposed individuals, most often in patients with human leukocyte antigen B8 (HLA-B8), human leukocyte antigen DR3 (HLA-DR3), human leukocyte antigen DRw52 (HLA-DRw52), and human leukocyte antigen DQ1 (HLA-DQ1).
How do you treat subacute cutaneous lupus erythematosus?
Standard therapy for subacute cutaneous lupus erythematosus (SCLE) includes topical corticosteroids and antimalarials such as hydroxychloroquine or chloroquine. In patients with skin lesions refractory to hydroxychloroquine monotherapy, adding quinacrine can improve response.
What are the symptoms of subcutaneous lupus?
Subacute cutaneous lupus often creates red, ring-shaped or raised lesions on your neck, back or chest. Acute cutaneous lupus has been termed the “butterfly rash” because it causes a red rash on your cheeks and nose that resembles butterfly wings.
Does subacute cutaneous lupus itch?
Subacute cutaneous lupus may be a sign of systemic lupus, but it can also develop on its own. Most of the time, lesions aren’t itchy or painful, and they rarely cause scarring after they heal.
Can cutaneous lupus be cured?
Three types of cutaneous lupus cause different rashes to appear. The rashes often result from sun exposure. There’s no cure for skin lupus. Providers treat it with drugs and lifestyle changes.
Is subacute cutaneous lupus an autoimmune disease?
What is Cutaneous Lupus? Cutaneous lupus erythematosus, the skin-related form of lupus, affects people with systemic lupus erythematosus (SLE), but can also occur on its own. Cutaneous lupus erythematosus is an autoimmune disorder that affects millions of people worldwide.
What are symptoms of subcutaneous lupus?
The general signs and symptoms of cutaneous lupus erythematosus include the following: Sudden onset of fever without any cause. Body weakness and fatigue. Malaise or a general feeling of discomfort. Development of skin rashes. Increased sensitivity to sunlight. Swelling of the lymph nodes.
What causes cutaneous lupus?
Like systemic lupus, cutaneous lupus is caused by an autoimmune response, meaning the body attacks its own tissues and organs. In cutaneous lupus, the immune system targets skin cells, causing inflammation that leads to red, thick, and often scaly rashes and sores that may burn or itch.
Which is a symptom of SLE?
People who have SLE may experience a range of symptoms, such as: skin problems, including rashes and tiny red spots. fatigue. fever. painful or swollen joints. weight loss. sun sensitivity.
Can cutaneous lupus turn into systemic lupus?
In approximately 10% of the cases of cutaneous lupus, it evolves and develops into systemic lupus. However, this can’t be predicted or prevented from happening. In approximately 10% of the cases of cutaneous lupus, it evolves and develops into systemic lupus. However, this can’t be predicted or prevented from happening.