How does panhypopituitarism affect the pituitary gland?
How does panhypopituitarism affect the pituitary gland?
Effects of panhypopituitarism may be gradual, or sudden and dramatic. Pituitary hormone production is regulated by the hypothalamus the area just above the pituitary that helps regulate hormone release from the gland. Reduced hormone output could be due to a problem with either the hypothalamus or the pituitary gland.
What do you need to know about panhypopituitarism in children?
Panhypopituitarism in Children 1 Panhypopituitarism is a condition in which the production… 2 Causes of panhypopituitarism. Pituitary hormone production is regulated by the hypothalamus… 3 Signs and symptoms of panhypopituitarism. Symptoms of panhypopituitarism vary widely,… 4 Testing and diagnosis for panhypopituitarism. Your doctor…
How is radiation therapy used to treat panhypopituitarism?
Radiation therapy may be used to kill tumor cells or to keep them from growing. Radiation therapy for a pituitary tumor must be narrowly targeted to minimize damage to nearby brain tissue. For most children and adolescents with panhypopituitarism, treatment with hormone replacement therapy is effective in restoring normal hormone levels.
Effects of panhypopituitarism may be gradual, or sudden and dramatic. Pituitary hormone production is regulated by the hypothalamus the area just above the pituitary that helps regulate hormone release from the gland. Reduced hormone output could be due to a problem with either the hypothalamus or the pituitary gland.
What are the symptoms of panhypopituitarism in children?
As a child of 6, he’d undergone surgery and radiation therapy to treat a malignant anterior pituitary gland tumor. This resulted in a deficiency of all anterior pituitary gland hormones. Called panhypopituitarism, this disorder includes deficiencies in growth hormone, thyroid-stimulating hormone, and adrenocorticotropic hormone.
When to use glucocorticoid replacement for panhypopituitarism?
If hypothyroidism occurs concurrently with adrenal crisis, glucocorticoid replacement should be provided before thyroid hormone replacement because of the increased metabolic demand for cortisol. 7 Diagnostic tests for panhypopituitarism include magnetic resonance imaging (MRI) and computed tomography (CT).
Why is LR at risk for panhypopituitarism?
The excision of a pituitary tumor and radiation therapy placed LR at risk for panhypopituitarism due to damage of the pituitary gland and resulting deficiency of anterior pituitary hormones.