Common questions / 30/04/2020

Can stavudine and zidovudine be taken together?

zidovudine stavudine Ask your doctor before using zidovudine together with stavudine. Using these medications together may cause either medication to be less effective. Contact your doctor if your condition worsens.

Is Combivir still used?

Yes, Combivir is still used by many people throughout the world. It’s not a first-choice option for people starting HIV ARV therapy, but many people have chosen to stay on Combivir since it works well for them and a generic version is available.

Why zidovudine with stavudine combination is not recommended?

The combination of stavudine (d4T) and didanosine (ddI), initially thought to be contraindicated because of the overlapping toxicity profiles of the 2 drugs, was found not only to be safe but to provide more potent antiviral activity than either drug administered alone [1, 2].

What is the use of lamivudine and zidovudine tablets?

Lamivudine and zidovudine are antiviral medications that prevent human immunodeficiency virus (HIV) from multiplying in your body. Lamivudine and zidovudine is a combination medicine used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS).

Is lamivudine a nucleoside?

Lamivudine is a nucleoside analogue that is phosphorylated to lamivudine triphosphate by cellular kinases. Lamivudine inhibits the reverse transcriptase of both HBV and HIV, and is indicated for the treatment of HIV and chronic HBV infection.

How often should you take a Combivir tablet?

The usual dosage of Combivir tablets is one tablet, twice a day. Your Combivir tablets should be swallowed with a drink of water. Do not halve the tablet. Your doctor or pharmacist will be able to tell you when you should take your Combivir tablets.

What’s the difference between Combivir and zidovudine?

COMBIVIR tablets are combination tablets containing lamivudine and zidovudine. Lamivudine (EPIVIR) and zidovudine (RETROVIR, azidothymidine, AZT, or ZDV) are synthetic nucleoside analogues with activity against HIV-1. COMBIVIR tablets are for oral administration.

How is Combivir used in the treatment of HIV?

Indications and Usage for Combivir. Combivir, a combination of 2 nucleoside analogues, is indicated in combination with other antiretrovirals for the treatment of human immunodeficiency virus type 1 (HIV‑1) infection.

Can you take Combivir with or without food?

Take Combivir exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. You may take this medicine with or without food. Use all HIV medications as directed and read all medication guides you receive.