Recommendations / 14/06/2021

Can Dilantin and phenobarbital be given together?

Using phenytoin together with PHENobarbital may affect your seizure control. You may need dose adjustments or special tests in order to safely take both medications together. This combination may alter phenytoin levels.

What are the side effects of Dilantin 100 mg?

Common side effects of Dilantin include:

headache,
nausea,
vomiting,
constipation,
dizziness,
spinning sensation,
drowsiness,
slurred speech,

What is phenobarbital drug used for?

Phenobarbital is used to control seizures. Phenobarbital is also used to relieve anxiety. It is also used to prevent withdrawal symptoms in people who are dependent (‘addicted’; feel a need to continue taking the medication) on another barbiturate medication and are going to stop taking the medication.

What are the long-term effects of taking phenobarbital?

Phenobarbital and phenytoin have good antiepileptic effect, but clinically significant untoward effects occur during their long-term use. Phenobarbital may cause hyperactivity, behavioral problems, sedation, and even dementia; these effects are dose related to some extent.

How many mg of phenytoin are in Dilantin?

Dosages of Phenytoin: 1 100 mg 2 200 mg 3 300 mg

How often should I take Dilantin extended oral capsules?

Once-a-day dosage: In adults, if seizure control is established with divided doses of three 100-mg DILANTIN (extended phenytoin sodium capsules, USP) daily, once-a-day dosage with 300 mg of DILANTIN (extended phenytoin sodium capsules, USP) may be considered.

What kind of salt is in Dilantin extended capsules?

Dilantin extended capsules and parenteral Dilantin are formulated with the sodium salt of phenytoin.

How many mg of phenobarbital can you take in one day?

Adult Oral Dosage: 1. Daytime sedative: 30 to 120 mg daily in 2 to 3 divided doses. 2. Bedtime hypnotic: 100 to 320 mg. 3. Anticonvulsant: 50 to 100 mg 2 to 3 times daily. Dosages of phenobarbital must be individualized with full knowledge of their particular characteristics and recommended rate of administration.

How much phenytoin is in a Dilantin capsule?

Each Dilantin— 100 mg (extended phenytoin sodium capsule, USP)—contains 100 mg phenytoin sodium. Also contains lactose monohydrate, NF; confectioner’s sugar, NF; talc, USP; and magnesium stearate, NF. The capsule body contains titanium dioxide, USP and gelatin, NF.

Are there any side effects of prescribing Dilantin?

Anyone considering prescribing Dilantin or any other AED must balance the risk of suicidal thoughts or behavior with the risk of untreated illness. Epilepsy and many other illnesses for which AEDs are prescribed are themselves associated with morbidity and mortality and an increased risk of suicidal thoughts and behavior.

Why does Dilantin lower phenytoin levels during pregnancy?

Decreased serum concentrations of phenytoin may occur during pregnancy because of altered phenytoin pharmacokinetics. Periodic measurement of serum phenytoin concentrations should be performed during pregnancy, and the DILANTIN dosage should be adjusted as necessary.