Are there any side effects to the Increlex injection?

Are there any side effects to the Increlex injection?

Benzyl alcohol, a preservative in INCRELEX ®, can cause serious side effects, including death in infants. Low blood sugar (hypoglycemia); injection site reactions; allergic reactions; and enlarged tonsils. These are not all the side effects of INCRELEX ®.

When is Increlex not used for growth promotion?

Increlex should not be used for growth promotion in patients with closed epiphyses. Increlex is contraindicated in pediatric patients with malignant neoplasia or a history of malignancy [see Warnings and Precautions (5.7) and Adverse Reactions (6.3) ].

Are there any side effects to Increlex for IGFD?

Anti-IGF-1 antibodies were present at one or more of the periodic assessments in 14 of 23 children with Primary IGFD treated for 2 years. However, no clinical consequences of these antibodies were observed (e.g., attenuation of growth).

What are the side effects of continuous infusion of insulin?

The risk for developing hypoglycemia is higher in patients receiving intensive or continuous infusion insulin therapy. The association between insulin and dyslipidemia is currently being evaluated. Permanent neuropsychological impairment has been associated with recurrent episodes of severe hypoglycemia.

Benzyl alcohol, a preservative in INCRELEX ®, can cause serious side effects, including death in infants. Low blood sugar (hypoglycemia); injection site reactions; allergic reactions; and enlarged tonsils. These are not all the side effects of INCRELEX ®.

Increlex should not be used for growth promotion in patients with closed epiphyses. Increlex is contraindicated in pediatric patients with malignant neoplasia or a history of malignancy [see Warnings and Precautions (5.7) and Adverse Reactions (6.3) ].

Anti-IGF-1 antibodies were present at one or more of the periodic assessments in 14 of 23 children with Primary IGFD treated for 2 years. However, no clinical consequences of these antibodies were observed (e.g., attenuation of growth).

What’s the generic name for the drug Increlex?

Generic Name: mecasermin (ME ka SER min) Brand Names: Increlex. Medically reviewed on May 14, 2018. Increlex (mecasermin) is a man-made form of insulin-like growth factor-1 (IGF-1), a substance that is normally produced in the body. IGF-1 is important for the growth of bones and muscles.