Where is tuberculosis found today?

Where is tuberculosis found today?

TB occurs in every part of the world. In 2019, the largest number of new TB cases occurred in the WHO South-East Asian region, with 44% of new cases, followed by the WHO African region, with 25% of new cases and the WHO Western Pacific with 18%. In 2019, 87% of new TB cases occurred in the 30 high TB burden countries.

Which 5 states are most affected by TB?

• In 2019, the majority (51%) of U.S. TB cases continued to be reported from 4 states: California (23.7%), Texas (13.0%), New York (8.5%), and Florida (6.3%).
• In 2018, the most recent data available, 542 deaths in the United States were attributed to TB. This is an increase from 515 deaths attributed to TB in 2017.

Where are the highest burdens of MDR-TB?

More than half of the global burden of MDR-TB is currently in three countries: India, China, and the Russian Federation. • Despite recent improvements in early identification and enrollment into treatment, high-burden countries often lack the resources needed to ensure quality of care for treatment success.

Is there any new evidence for MDR RR TB?

New evidence on the effectiveness and safety of all-oral shorter regimens for MDR/RR-TB treatment was made available to WHO during 2019, specifically from the Nix-TB study and from observational studies and programmatic data. These data addressed some of the evidence gaps identified in 2018 and were felt to have direct public health benefit.

What is the risk of TB if there is no treatment?

TB infection and no risk factors. About 10% over a lifetime For people with TB infection, no risk. factors, and no treatment, the risk is about 5% in the first 2 years after infection and about 10% over a lifetime.

Is the BPAL regimen appropriate for patients with XDR-TB?

No. The BPaL regimen is relevant in patients with confirmed XDR-TB who have not had previous exposure to bedaquiline and linezolid for more than two weeks. This regimen is not appropriate for programmatic use worldwide until additional evidence on efficacy and safety has been generated.