What is the structure of monocyte?
What is the structure of monocyte?
The monocyte is a spherical cell with prominent surface ruffles and blebs when examined by scanning electron microscopy. As the monocyte enters the tissue and differentiates into a macrophage, the cell volume and number of cytoplasmic granules increase.
What is the structure and function of monocyte?
Monocytes are a type of white blood cell. Like other white blood cells, monocytes are important in the immune system’s ability to destroy invaders, but also in facilitating healing and repair. Monocytes are formed in the bone marrow and are released into peripheral blood, where they circulate for several days.
What are the characteristics of monocyte?
Monocytes have generally lighter staining nuclei than do other leukocytes. The nucleus stains a pale bluish-violet, and the chromatin is fine. Overall, the nucleus has a soft, spongy, three-dimensional appearance, in contrast to the hard, flat nucleus of the large lymphocyte and the densely clumped nucleus of the band.
What is the role of monocyte?
Monocytes are a critical component of the innate immune system. They are the source of many other vital elements of the immune system, such as macrophages and dendritic cells. Monocytes play a role in both the inflammatory and anti-inflammatory processes that take place during an immune response.
What is meant by monocyte?
Listen to pronunciation. (MAH-noh-site) A type of immune cell that is made in the bone marrow and travels through the blood to tissues in the body where it becomes a macrophage or a dendritic cell.
What are the properties of a monocyte cell?
Monocytes exhibit the characteristic properties of phagocytosis—namely, movement, adherence, endocytosis, and microbial activity. Monocytes are capable of directed movement (chemotaxis) in response to substances (chemokines) produced by bacteria or by accessory cells at the site of injury or invasion.
Is the monocyte count part of the complete blood count?
A monocyte count is part of a complete blood count and is expressed either as a percentage of monocytes among all white blood cells or as absolute numbers. Both may be useful but these cells became valid diagnostic tools only when monocyte subsets are determined. Monocytosis is the state of excess monocytes in the peripheral blood.
What causes elevated monocytes in white blood cells?
Elevated monocyte counts may be due to a problem with blood cell production. In certain cases, the excess is due to a malignancy, such as certain types of leukemia. Low numbers of monocytes may be seen after chemotherapy, usually because your overall white blood cell count is low. 3 Understanding Common Blood Tests and What They Mean
Why are monocytes darker than other leukocytes?
Because monocytes are extremely motile cells, blunt pseudopods may be seen. These should not be confused with the apparent cytoplasmic projections produced when large lymphocytes are indented by surrounding cells. Monocytes have generally lighter staining nuclei than do other leukocytes.