What is the classification of leprosy?

What is the classification of leprosy?

Hear this out loudPauseLeprosy has traditionally been classified into two major types, tuberculoid and lepromatous. Patients with tuberculoid leprosy have limited disease and relatively few bacteria in the skin and nerves, while lepromatous patients have widespread disease and large numbers of bacteria.

What are the two classification of leprosy?

Hear this out loudPauseAccording to this system, based on immunological, histopathological and microbiological parameters, leprosy patients have been grouped as lepromatous leprosy (LL), borderline lepromatous leprosy (BL), midborderline (BB), borderline tuberculoid (BT) and tuberculoid leprosy (TT).

WHO recommended treatment for leprosy?

What is the WHO recommended multidrug regimen for treatment of leprosy?

Age Group Drug Dosage and Frequency
Adult Clofazimine 300 mg once a month and 50 mg daily
Dapsone 100 mg daily
Children (10-14 years) Rifampicin 450 mg once a month
Clofazimine 150 mg once a month, 50 mg on alternate days

Who Paucibacillary leprosy classification?

Hear this out loudPauseClassification (clinical): Paucibacillary single lesion leprosy: 1 skin lesion. Paucibacillary leprosy: 2 to 5 patches or lesions on the skin. Multibacillary leprosy: >5 patches or lesions on the skin.

What is TT leprosy?

Hear this out loudPausePatients with tuberculoid leprosy (TT) are resistant to the bacillus and infection is localised. Patients with lepromatous leprosy (LL) are extremely sensitive to the bacillus and the infection is disseminated. Borderline forms (BT, BB, BL) are between the two ends of the spectrum (TT and LL).

What is BT in leprosy?

Hear this out loudPauseBorderline-tuberculoid leprosy (BT) is usually associated with more numerous lesions than tuberculoid leprosy, and these are usually smaller. Daughter (satellite) patches may develop. Hypoesthesia and impairment of hair growth within the lesions are often present.

How are the different types of leprosy classified?

Thus, the classification in leprosy has faced marked difficulties in evolving a satisfactory universally acceptable clinical system of classification. In the literature, different classification systems are available based on clinical, bacteriological, pathological, immunological and therapeutic purposes

How is the diagnosis of multibacillary leprosy made?

Multibacillary leprosy includes LL, BL and BB forms and paucibacillary leprosy includes the TT and BT forms of the Ridley-Jopling classification system. – Laboratory diagnosis is based on the detection of acid-fast bacilli in a Ziehl-Neelsen stained nasal smear and skin-split smear taken from the ear lobe or from a skin lesion.

How is leprosy classified by Ridley-Jopling classification?

The criteria of skin-smear positivity at any site resulted in a significantly greater frequency (57%) of patients whose leprosy was classified as PB by lesion counting who were considered to have MB leprosy by Ridley-Jopling classification (38%; P = .04) or by a BI value ≥2 (31%; P = .005).

What is the best way to treat leprosy?

Countries where leprosy is endemic have a control programme. Check national recommendations. Note: the monthly doses of rifampicin and clofazimine are administered under direct observation by medical staff whereas the daily doses of clofazimine and dapsone are taken by the patient at home.

What kind of classification is used for leprosy?

The clinical system of classification for the purpose of treatment includes the use of number of skin lesions and nerves involved as the basis for grouping leprosy patients into multibacillary (MB) and paucibacillary (PB) leprosy.

The criteria of skin-smear positivity at any site resulted in a significantly greater frequency (57%) of patients whose leprosy was classified as PB by lesion counting who were considered to have MB leprosy by Ridley-Jopling classification (38%; P = .04) or by a BI value ≥2 (31%; P = .005).

Can a leprosy patient be treated with multibacillary disease?

While classifying leprosy, it is particularly important to ensure that patients with multibacillary disease are not treated with the regimen for the paucibacillary form of the disease.

How many leprosy patients are at risk of undertreatment?

Of those whose leprosy was classified as paucibacillary, 38%–51% of patients had multibacillary leprosy according to classic criteria and were thus at risk of undertreatment according to World Health Organization recommendations.