What does it mean when your gamma globulin is high?

What does it mean when your gamma globulin is high?

Increased gamma globulin proteins may indicate: Blood cancers, including multiple myeloma, Waldenström macroglobulinemia, lymphomas, and chronic lymphocytic leukemias. Chronic inflammatory disease (for example, rheumatoid arthritis) Acute infection.

What is the function of gamma globulin in blood?

Overview. Immunoglobulin (also called gamma globulin or immune globulin) is a substance made from human blood plasma. The plasma, processed from donated human blood, contains antibodies that protect the body against diseases.

What if gamma globulin is low?

Low levels of gamma globulins suggest the under-production of antibodies as found in certain genetic diseases (bubble boy agammaglobulinemia) and leukemia. Other tests can more accurately identify which fraction or sub-component of gamma globulins may be abnormal (protein immunofixation, free kappa or lambda chains).

What does low gamma globulin level mean?

Low levels of gamma globulin, or hypogammaglobulinemia, typically mean that a person has some sort of immune disorder or deficiency, such as common variable immunodeficiency (CVID). A proliferation of abnormal gamma globulin, or paraproteins, is also a sign of immune malfunction.

What causes low globulin blood test?

Underlying Causes of Low Globulin Levels in Body. Low globulin levels can be caused by several diseases, like kidney disease. The level of protein found in the urine may even be negligible. This occurs when the glomerulus, or formation of urine, prevents proteins, blood cells and other larger structures from passing.

Is IgG and gamma globulin the same thing?

1 Answer. In the past the terms were used interchangeably, but there is a difference . There are IgGs in the gamma globulin fraction along with the other gamma globulin proteins but only gamma globulin G is in the IgG fraction .