How would hemophilia affect a person who has it?
How would hemophilia affect a person who has it?
Hemophilia can result in: Bleeding within joints that can lead to chronic joint disease and pain. Bleeding in the head and sometimes in the brain which can cause long term problems, such as seizures and paralysis. Death can occur if the bleeding cannot be stopped or if it occurs in a vital organ such as the brain.
How can a person’s DNA determine if they have hemophilia?
It is unlikely that genetic testing is needed to diagnose hemophilia. A number of cheaper and quicker blood tests exist that can successfully diagnose the disease. It is possible to use genetic testing to identify the mutations on the F8 or F9 genes that have caused either hemophilia A or B.
What happens in the DNA to cause hemophilia?
Hemophilia A and hemophilia B are inherited in an X-linked recessive pattern . The genes associated with these conditions are located on the X chromosome, which is one of the two sex chromosomes . In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition.
When do you find out if you have hemophilia?
However, those with mild hemophilia may not be diagnosed until adulthood when they experience a bleeding episode due to trauma or surgery. Hemophilia is diagnosed with blood tests to determine if clotting factors are missing or at low levels, and which ones are causing the problem.
Can a person with no symptoms of hemophilia bleed?
Most women with the defective gene are simply carriers and experience no signs or symptoms of hemophilia. But some carriers can experience bleeding symptoms if their clotting factors are moderately decreased. The biggest risk factor for hemophilia is to have family members who also have the disorder.
How are blood clotting factors measured for hemophilia?
This test measures how long it takes for blood to clot. It measures the clotting ability of factors VIII (8), IX (9), XI (11), and XII (12). If any of these clotting factors are too low, it takes longer than normal for the blood to clot.
Can a low hemoglobin count be sign of hemophilia?
However, if a person with hemophilia has unusually heavy bleeding or bleeds for a long time, the hemoglobin and the red blood cell count can be low. This test measures how long it takes for blood to clot. It measures the clotting ability of factors VIII (8), IX (9), XI (11), and XII (12).
However, those with mild hemophilia may not be diagnosed until adulthood when they experience a bleeding episode due to trauma or surgery. Hemophilia is diagnosed with blood tests to determine if clotting factors are missing or at low levels, and which ones are causing the problem.
Most women with the defective gene are simply carriers and experience no signs or symptoms of hemophilia. But some carriers can experience bleeding symptoms if their clotting factors are moderately decreased. The biggest risk factor for hemophilia is to have family members who also have the disorder.
What is the normal severity level for hemophilia?
Severity Levels. The standard factor level is 100%. You can have a factor level between 50% and 200% and still be considered normal. In a person with hemophilia, the clotting factor level is much lower than the standard.
However, if a person with hemophilia has unusually heavy bleeding or bleeds for a long time, the hemoglobin and the red blood cell count can be low. This test measures how long it takes for blood to clot. It measures the clotting ability of factors VIII (8), IX (9), XI (11), and XII (12).